Otay Mesa Hotels, San Diego
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Our top choices for Otay Mesa hotels
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHGOtay Mesa
8.0 out of 10, Very good, (1,617 reviews)
"rooms clean and service great"
patricia
The price is AU$219
includes taxes & fees
15 Feb - 16 Feb
Quality Suites San Diego Otay Mesa
Quality Suites San Diego Otay MesaOtay Mesa
7.0 out of 10, Good, (1,000 reviews)
"Great staff.. location close to the airport!"
Vivian
The price is AU$162
includes taxes & fees
2 Feb - 3 Feb
Moxy San Diego Downtown/Gaslamp Quarter
Moxy San Diego Downtown/Gaslamp QuarterGaslamp Quarter, 24.4 km from Otay Mesa
9.0 out of 10, Wonderful, (1,002 reviews)
"I love this hotel! Staff, hotel, and room wonderful!"
Debbie
The price is AU$261
includes taxes & fees
12 Feb - 13 Feb
Westgate Hotel
Westgate Hotel24.9 km from Otay Mesa
9.0 out of 10, Wonderful, (1,006 reviews)
"Great stay"
ESMERALDA
Sea Harbor Hotel
Sea Harbor Hotel30.1 km from Otay Mesa
8.6 out of 10, Excellent, (1,002 reviews)
"Super clean rooms and a great location "
Mark
Fairfield Inn & Suites San Diego Old Town
Fairfield Inn & Suites San Diego Old TownOld Town San Diego, 29.4 km from Otay Mesa
8.8 out of 10, Excellent, (1,009 reviews)
"Great location, clean rooms, good breakfast"
Jingyi
The price is AU$236
includes taxes & fees
16 Feb - 17 Feb
Best Western Plus Bayside Inn
Best Western Plus Bayside Inn25.4 km from Otay Mesa
9.0 out of 10, Wonderful, (1,003 reviews)
"Excellent stay!"
D'ette
The price is AU$242
includes taxes & fees
22 Feb - 23 Feb
Super 8 by Wyndham San Diego Hotel Circle
Super 8 by Wyndham San Diego Hotel Circle28.8 km from Otay Mesa
7.2 out of 10, Good, (671 reviews)
"The rooms my son stayed at were very clean and so was all the staff. Had a great experience.😊🙏❤️🙌"
Mirna
The price is AU$119
includes taxes & fees
8 Feb - 9 Feb
Berkshire Motor Hotel
Berkshire Motor HotelNorth Park, 26.7 km from Otay Mesa
8.4 out of 10, Very good, (1,003 reviews)
"Clean, very chill easy check in"
Susana
The price is AU$146
includes taxes & fees
2 Feb - 3 Feb
La Pensione Hotel
La Pensione HotelLittle Italy, 25.8 km from Otay Mesa
8.6 out of 10, Excellent, (1,898 reviews)
"Great location and staff "
morgan
Courtyard by Marriott Old Town
Courtyard by Marriott Old TownOld Town San Diego, 29.7 km from Otay Mesa
8.6 out of 10, Excellent, (1,003 reviews)
"Our check in was amazing, all the staff were extremely friendly and helpful. We will be booking at this location when visiting Old Town. "
Velinda
The price is AU$251
includes taxes & fees
17 Feb - 18 Feb
Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town
Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town30.8 km from Otay Mesa
9.2 out of 10, Wonderful, (580 reviews)
"Great place to stay, nice room Highly recommended !!"
Wilfredo
The price is AU$195
includes taxes & fees
21 Feb - 22 Feb
Ocean Villa Inn
Ocean Villa InnOcean Beach, 33.7 km from Otay Mesa
8.0 out of 10, Very good, (1,151 reviews)
"Beds are super comfy clean and renovated"
Esmeralda
The price is AU$143
includes taxes & fees
3 Feb - 4 Feb
Springhill Suites San Diego Mission Valley
Springhill Suites San Diego Mission Valley28.2 km from Otay Mesa
9.2 out of 10, Wonderful, (1,002 reviews)
"Very friendly staff, quick check-in, spacious room, and very clean! Great place to stay! "
Jodi
The price is AU$279
includes taxes & fees
1 Mar - 2 Mar
Heritage Inn San Diego
Heritage Inn San Diego31.8 km from Otay Mesa
7.4 out of 10, Good, (1,225 reviews)
"It was clean an pretty close from airport"
Hortencia
The price is AU$104
includes taxes & fees
5 Feb - 6 Feb
Courtyard by Marriott San Diego Downtown Little Italy
Courtyard by Marriott San Diego Downtown Little ItalyLittle Italy, 25.5 km from Otay Mesa
9.0 out of 10, Wonderful, (322 reviews)
"Great place to stay "
Jacorey
The price is AU$240
includes taxes & fees
8 Feb - 9 Feb
Hilton Garden Inn San Diego Downtown/Bayside
Hilton Garden Inn San Diego Downtown/Bayside26.2 km from Otay Mesa
8.6 out of 10, Excellent, (1,242 reviews)
"Staff was great and always a nice stay, thank you!"
Edin
The price is AU$242
includes taxes & fees
6 Feb - 7 Feb
The Beau Downtown San Diego Gaslamp Quar
The Beau Downtown San Diego Gaslamp QuarGaslamp Quarter, 24.5 km from Otay Mesa
9.0 out of 10, Wonderful, (591 reviews)
"Clean room, friendly staff, great location."
Bruce
The price is AU$229
includes taxes & fees
5 Feb - 6 Feb
Gaslamp Plaza Suites
Gaslamp Plaza SuitesGaslamp Quarter, 24.6 km from Otay Mesa
9.0 out of 10, Wonderful, (1,030 reviews)
"Clean quiet friendly helpful staff convenient location will stay there again"
David
The price is AU$237
includes taxes & fees
6 Feb - 7 Feb
Hampton Inn & Suites San Diego Airport Liberty Station
Hampton Inn & Suites San Diego Airport Liberty Station29.2 km from Otay Mesa
9.2 out of 10, Wonderful, (1,717 reviews)
"Great place to stay for access to the airport, staff was super!"
Alison
The price is AU$279
includes taxes & fees
8 Feb - 9 Feb
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Our guide on where to stay in Otay Mesa
Find the best Otay Mesa areas for the activities you enjoy most. Learn more about Otay Mesa
Learn more about Otay Mesa
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Mission Beach
If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.
Pacific Beach
Get to Pacific Beach after the sun goes down because this is the place to be in San Diego for partying.
Gaslamp Quarter
The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.
Ocean Beach
With a secluded sunbathing beach, swimming-only beach, special surf beach, volleyball beach and dog beach, San Diego’s “OB” sure takes beaches seriously.
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