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Otay Mesa Hotels, San Diego

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Our top choices for Otay Mesa hotels

1. Quality Suites San Diego Otay Mesa

Quality Suites San Diego Otay Mesa
2.5 star property
Otay Mesa
7.2 out of 10, Good, (1,013 reviews)
"Very clean, bed was comfortable!"
United States
Michael A
The price is AU$182
includes taxes & fees
21 June - 22 June
Quality Suites San Diego Otay Mesa

2. Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2.5 star property
Otay Mesa
8.2 out of 10, Very good, (1,750 reviews)
"Clean, friendly staff, great breakfast!!"
United States
Flor
The price is AU$225
includes taxes & fees
28 June - 29 June
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

3. Valli Hi Motel

Valli Hi Motel
2.5 star property
7.9 km from Otay Mesa
8.4 out of 10, Very good, (1,027 reviews)
"Great place to stay."
United States
Allan
The price is AU$139
includes taxes & fees
21 June - 22 June
Valli Hi Motel

4. Ocean Villa Inn

Ocean Villa Inn
2.5 star property
Ocean Beach, 33.7 km from Otay Mesa
8.0 out of 10, Very good, (1,293 reviews)
"This is very pet friendly and staff is great"
United States
Arturo
The price is AU$270
includes taxes & fees
18 June - 19 June
Ocean Villa Inn

5. Studio 6 Suites San Ysidro, CA -San Diego South Bay

Studio 6 Suites San Ysidro, CA -San Diego South Bay
2.5 star property
6.9 km from Otay Mesa
8.0 out of 10, Very good, (1,682 reviews)
"It’s ok to stay one or two days"
United States
Valentina
The price is AU$127
includes taxes & fees
18 June - 19 June
Studio 6 Suites San Ysidro, CA -San Diego South Bay

6. Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
28.5 km from Otay Mesa
9.4 out of 10, Exceptional, (1,975 reviews)
"Always a great stay"
United States
Jeanette
The price is AU$197
includes taxes & fees
12 July - 13 July
Sycuan Casino Resort

7. Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG
3.5 star property
29.8 km from Otay Mesa
8.2 out of 10, Very good, (1,061 reviews)
"great stay"
United States
David
The price is AU$218
includes taxes & fees
29 June - 30 June
Crowne Plaza San Diego - Mission Valley by IHG

8. The Alcala Hotel Mission Valley/Seaworld

The Alcala Hotel Mission Valley/Seaworld
2.5 star property
30.2 km from Otay Mesa
8.0 out of 10, Very good, (232 reviews)
"Staff was great and rooms were nice."
United States
Brittney
The price is AU$246
includes taxes & fees
22 June - 23 June
The Alcala Hotel Mission Valley/Seaworld

9. Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
26.8 km from Otay Mesa
9.4 out of 10, Exceptional, (1,726 reviews)
"Beautiful hotel"
United States
Cuauhtemoc
The price is AU$405
includes taxes & fees
29 June - 30 June
Lafayette Hotel & Club

10. Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
16.9 km from Otay Mesa
9.2 out of 10, Wonderful, (3,872 reviews)
"Great stay"
United States
Cameron
The price is AU$279
includes taxes & fees
28 June - 29 June
Best Western Plus Marina Gateway Hotel

11. Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
28.1 km from Otay Mesa
8.4 out of 10, Very good, (3,525 reviews)
"Great location and shuttle service to and from the airport."
Canada
Malinda
The price is AU$330
includes taxes & fees
1 July - 2 July
Sheraton San Diego Resort

12. Best Western Americana Inn

Best Western Americana Inn
2.5 star property
8 km from Otay Mesa
8.8 out of 10, Excellent, (1,316 reviews)
"The breakfast was great, the staff was helpful, and the room was clean and spacious!"
United States
Christopher
The price is AU$197
includes taxes & fees
28 June - 29 June
Best Western Americana Inn

13. Heritage Inn San Diego

Heritage Inn San Diego
2.0 star property
31.8 km from Otay Mesa
7.4 out of 10, Good, (1,527 reviews)
The price is AU$112
includes taxes & fees
28 June - 29 June
Heritage Inn San Diego

14. Quality Inn San Diego I-5 Naval Base

Quality Inn San Diego I-5 Naval Base
2.5 star property
18.8 km from Otay Mesa
7.8 out of 10, Good, (959 reviews)
The price is AU$171
includes taxes & fees
28 June - 29 June
Quality Inn San Diego I-5 Naval Base

15. Best Western San Diego Pacific Beach/Mission Bay

Best Western San Diego Pacific Beach/Mission Bay
2.5 star property
33.6 km from Otay Mesa
8.2 out of 10, Very good, (431 reviews)
"Nice hotel."
United States
Aron
The price is AU$228
includes taxes & fees
29 June - 30 June
Best Western San Diego Pacific Beach/Mission Bay

16. Comfort Inn Sea World Area

Comfort Inn Sea World Area
3.5 star property
30.8 km from Otay Mesa
8.6 out of 10, Excellent, (3,782 reviews)
"The location of the hotel is convenient repertory people who want to visit Seaworld."
United States
Bektursun
The price is AU$220
includes taxes & fees
29 June - 30 June
Comfort Inn Sea World Area

17. Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
31.3 km from Otay Mesa
7.4 out of 10, Good, (4,295 reviews)
"Clean room, staff was very helpful, parking was easy and accessible!"
United States
Hector
The price is AU$207
includes taxes & fees
29 June - 30 June
Wyndham Garden San Diego Near SeaWorld

18. Days Inn by Wyndham San Diego-East/El Cajon

Days Inn by Wyndham San Diego-East/El Cajon
2.0 star property
27.3 km from Otay Mesa
7.8 out of 10, Good, (1,001 reviews)
"Rooms were cheap clean property was clean convenient close to where I was working"
United States
James
The price is AU$158
includes taxes & fees
28 June - 29 June
Days Inn by Wyndham San Diego-East/El Cajon

19. Berkshire Motor Hotel

Berkshire Motor Hotel
2.5 star property
North Park, 26.7 km from Otay Mesa
8.4 out of 10, Very good, (1,002 reviews)
"Clean and the guy at the front desk is very friendly"
United States
Carlos
The price is AU$201
includes taxes & fees
21 June - 22 June
Berkshire Motor Hotel

20. San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay, 33.1 km from Otay Mesa
8.6 out of 10, Excellent, (1,483 reviews)
"We have stayed here before, good location, clean rooms, great staff."
United States
Lance
The price is AU$528
includes taxes & fees
6 July - 7 July
San Diego Mission Bay Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in Otay Mesa

Find the best Otay Mesa areas for the activities you enjoy most. Learn more about Otay Mesa
Learn more about Otay Mesa

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Pacific Beach

Get to Pacific Beach after the sun goes down because this is the place to be in San Diego for partying.

Mission Beach

If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Ski Beach are top sights worth seeing.

Top Otay Mesa Hotel Reviews

Frequently asked questions

What's it like in Otay Mesa?
Otay Mesa is a neighbourhood that travellers like for its beaches, restaurants and shopping.
Where is the best hotel for a stay in Otay Mesa?
Based on our traveller data, Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is one of the top choices for your stay in Otay Mesa. This hotel offers free breakfast and an outdoor pool.
If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?
Yes! Most room reservations are refundable provided that you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Add dates, click "Search", then filter by "fully refundable" to view top deals in Otay Mesa.
What is there to do in this San Diego neighbourhood?
A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.

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